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KIMIHAUORA Health Centre
Address: Mangatawa Lane, Mount Maunganui, New Zealand
Mail address: PO Box 4341 Mount Maunganui South, North Island, New Zealand
Telephone: (07) 574 8967 Facsimile: (07) 574 8964
© Kimihauora Health Centre 2004
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Historical Background
Some
thirty years ago, doctors from Tauranga expressed much concern at the high
incidence of stomach cancer of a diffuse type within a Maori population,
thus sparking an interest from other cancer experts as to why this was occurring.
At that time it was believed that this type of cancer was hereditary. Specific
age groups were identified as being afflicted between the 14-30 age group
which prompted the undertaking of investigations and many years of research
by medical and other professionals, some from as far field as Otago, Wanganui
and Palmerston North, each presenting their own theories, finally concluding
that this disease is unique to a population of Maori and Scottish descent.
In 1994 a project, initiated by the whanau, was
established with the aim of reducing the high incidence of gastric cancer
within the Maori population and to protect the whanau and their taonga
throughout this process.
In 1995 a pilot study began with 105 volunteering local whanau members at
risk with the disease.
This involved the collection of tissue samples and whakapapa information.
The aim of this study was to identify a gene susceptible to the disease,
identification of this gene would enable early intervention strategies to
be targeted to those at greatest risk of developing stomach cancer.
Hence the Kimihauora Unit entered into a partnership
agreement with Otago University, what was to be done and what was not to
be done. The principal investigator being Dr Parry Guilford and Professor
Anthony Reeve.
In 1997 a gene mutation was identified and genetic testing began. From there
we formed the Aotearoa National Gastric cancer project to service a Rotorua
whanau, we are also assisting in the setting up of 3 other places, those
being Wanganui, East Coast and Taranaki.
Patients with the familial gastric cancer mutation face
a 70% likelihood of developing CA during their lifetime is between 15-35
in both male and female. The local family have been recorded as having the
largest Gastric Cancer pedigree in the world.
We have now entered into another research partnership agreement with the
Molecular Bio Science Dept, of Massey University. The principal investigators,
Dr Paul O'Toole and Senior Lab Technician, Natasha Forrester, Whanau Research
Coordinator, Aroha Kakau.
The aim of this research is to investigate the harmful
effects of a stomach bacteria "Helicobactor Pylori" which could
be a major factor to causing stomach cancer.
The Project has blossomed and is now coming in to the second stage, and that
is finding a cure for the disease.